Prototypical Stressors

Showing 501 to 525 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

238	Methoxyfenozide	Methoxyfenozide, CAS-RN: 161050-58-4, DTXSID3032628	2 AOPs 4: Ecdysone receptor agonism leading to mortality via suppression of Ftz-f1 342: Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade
353	Methoxyflurane	Methoxyflurane, CAS-RN: 76-38-0, DTXSID7025556	260: CYP2E1 activation and formation of protein adducts leading to neurodegeneration
38	Methyl methanesulfonate	Methyl methanesulfonate, CAS-RN: 66-27-3, DTXSID7020845	None
650	Methyl parathion	Methyl parathion, CAS-RN: 298-00-0, DTXSID1020855	3 AOPs 405: Organo-Phosphate Chemicals induced inhibition of AChE leading to impaired cognitive function 450: Inhibition of AChE and activation of CYP2E1 leading to sensory axonal peripheral neuropathy and mortality 561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
39	Methyl-l-N'-nitro-N-nitroguanidine	Methylnitronitrosoguanidine, CAS-RN: 70-25-7, DTXSID2020846	None
359	Methylcarbino		None
639	Methyldihydrotestosterone		376: Androgen receptor agonism leading to male-biased sex ratio
40	Methylmercuric(II) chloride	Methylmercuric(II) chloride, CAS-RN: 115-09-3, DTXSID5020813	17: Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins involved in protection against oxidative stress during brain development leads to impairment of learning and memory
218	metofluthrin	Metofluthrin, CAS-RN: 240494-70-6, DTXSID4034738	107: Constitutive androstane receptor activation leading to hepatocellular adenomas and carcinomas in the mouse and the rat
830	Metolachlor	Metolachlor, CAS-RN: 51218-45-2, DTXSID4022448	561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
855	Metribuzin	Metribuzin, CAS-RN: 21087-64-9, DTXSID6024204	567: Binding to plastoquinone B site leading to decreased population growth rate via photosystem II inhibition
574	Metyrapone	Metyrapone, CAS-RN: 54-36-4, DTXSID1023314	349: Inhibition of 11β-hydroxylase leading to decresed population trajectory
289	Miconazole	Miconazole, CAS-RN: 22916-47-8, DTXSID6023319	None
799	Milrinone		2 AOPs 554: β-adrenergic receptor agonists leading to arrhythmias. 558: Phosphodiesterase inhibition leading to heart failure
486	minocycline	Minocycline, CAS-RN: 10118-90-8, DTXSID1045033	277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
676	Mitochondrial ETC inhibitors		None
854	ML385		615: Suppression of Keap1 cysteine oxidation leading to liver inflammation
684	Molinate	Molinate, CAS-RN: 2212-67-1, DTXSID6024206	None
64	Mono(2-ethylhexyl) phthalate		457: Succinate dehydrogenase inhibition leading to increased insulin resistance through reduction in circulating thyroxine
569	monobenzyl phthalate		None
692	Montelukast	Montelukast, CAS-RN: 158966-92-8, DTXSID9023334	None
222	MPP+		3: Inhibition of the mitochondrial complex I of nigro-striatal neurons leads to parkinsonian motor deficits
403	MS-275	MS-275, CAS-RN: 209783-80-2, DTXSID0041068	274: Histone deacetylase inhibition leads to impeded craniofacial development
306	Multi-walled carbon nanotubes		409: Frustrated phagocytosis leads to malignant mesothelioma
847	Muristerone A		342: Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade