Prototypical Stressors

Showing 226 to 250 of 853 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

510	colchemid		None
124	Colchicine	Colchicine, CAS-RN: 64-86-8, DTXSID5024845	106: Chemical binding to tubulin in oocytes leading to aneuploid offspring
332	Colistin	Colistin, CAS-RN: 1066-17-7, DTXSID1040663	257: Receptor mediated endocytosis and lysosomal overload leading to kidney toxicity
196	coumachlor	Coumachlor, CAS-RN: 81-82-3, DTXSID8041797	187: Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage
197	coumatetralyl	Coumatetralyl, CAS-RN: 5836-29-3, DTXSID8041799	187: Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage
527	COVID-19		None
848	Cucurbitacin B		606: Ecdysone receptor antagonism leading to mortality via inhibition of chitin synthase 1
849	Cucurbitacin D		606: Ecdysone receptor antagonism leading to mortality via inhibition of chitin synthase 1
842	CuO nanoparticles		590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
612	curcumin	Curcumin, CAS-RN: 458-37-7, DTXSID8031077	277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
244	Cyasterone		4: Ecdysone receptor agonism leading to mortality via suppression of Ftz-f1
783	Cyclizine	Cyclizine, CAS-RN: 82-92-8, DTXSID4022864	504: SULT1E1 inhibition leading to uterine adenocarcinoma via increased estrogen availability at target organ level
689	Cycloate	Cycloate, CAS-RN: 1134-23-2, DTXSID6032356	None
748	Cyclopamine	Cyclopamine, CAS-RN: 4449-51-8, DTXSID6043709	None
294	Cyclosporin		2 AOPs 154: Inhibition of Calcineurin Activity Leading to Impaired T-Cell Dependent Antibody Response 622: Calcineurin inhibitor induced nephrotoxicity leading to kidney failure
591	Cyclosporin, FK506, Basiliximab, PFOA (perfluorooctanoic acid)		None
108	Cyfluthrin	Cyfluthrin, CAS-RN: 68359-37-5, DTXSID5035957	None
135	Cyp2f2 substrates		None
103	Cypermethrin	Cypermethrin, CAS-RN: 52315-07-8, DTXSID1023998	561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
560	Cyproterone acetate	Cyproterone acetate, CAS-RN: 427-51-0, DTXSID5020366	None
484	D-2-hydroxyglutarate		None
121	D-limonene	D-Limonene, CAS-RN: 5989-27-5, DTXSID1020778	None
75	Daidzein	7,4'-Dihydroxyisoflavone, CAS-RN: 486-66-8, DTXSID9022310	None
631	Danger Associated Molecular Patters (DAMPs)		377: Dysregulated prolonged Toll Like Receptor 9 (TLR9) activation leading to Multi Organ Failure involving Acute Respiratory Distress Syndrome (ARDS)
312	Dazornet		242: Inhibition of lysyl oxidase leading to enhanced chronic fish toxicity