Key Event Relationships (KERs)

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Showing 2201 to 2225 of 3081 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
2651 1496: Increased proinflammatory mediators 398: Activation, Dendritic Cells Apr 28, 2022 Aug 1, 2022
3052 1496: Increased proinflammatory mediators 1439: Systemic acute phase response Sep 19, 2023 Jan 20, 2025
1550 1344: Increased, seizure 1363: Increased, epilepsy Jun 2, 2017 Jun 2, 2017
644 626: Increased, serotonin (5-HT) 627: Decreased, anxiety Nov 29, 2016 Dec 3, 2016
1207 626: Increased, serotonin (5-HT) 1160: Increased, mantel display Nov 29, 2016 Dec 3, 2016 None
1209 626: Increased, serotonin (5-HT) 1162: Increased, cilia movement Nov 29, 2016 Dec 3, 2016 None
1212 626: Increased, serotonin (5-HT) 1161: Increased, oocyte maturation Nov 29, 2016 Dec 3, 2016
1327 626: Increased, serotonin (5-HT) 1142: Increased, valve movement Jan 17, 2017 Jan 17, 2017
1332 626: Increased, serotonin (5-HT) 625: Increased, muscular waves in foot Jan 30, 2017 Jan 30, 2017
1333 626: Increased, serotonin (5-HT) 621: Increase, cilia movement Jan 30, 2017 Jan 30, 2017
1336 626: Increased, serotonin (5-HT) 1256: increased mantel display Jan 30, 2017 Jan 30, 2017
636 620: Increased, serotonin (5-HT) 1 621: Increase, cilia movement Nov 29, 2016 Dec 3, 2016 None
640 620: Increased, serotonin (5-HT) 1 625: Increased, muscular waves in foot Nov 29, 2016 Dec 3, 2016 None
1172 620: Increased, serotonin (5-HT) 1 1142: Increased, valve movement Nov 29, 2016 Dec 3, 2016 None
1186 620: Increased, serotonin (5-HT) 1 1145: Decreased, gametogenesis Nov 29, 2016 Dec 3, 2016 None
1189 620: Increased, serotonin (5-HT) 1 622: Increased, locomotion Nov 29, 2016 Dec 3, 2016 None
1192 620: Increased, serotonin (5-HT) 1 1147: increased or inappropriate, mantel display Nov 29, 2016 Dec 3, 2016 None
1524 1397: Increased, serotonin transporter activity 1398: Increased, intracellular serotonin Jun 1, 2017 Jun 1, 2017
1528 1397: Increased, serotonin transporter activity 1347: Decreased, extracellular serotonin Jun 1, 2017 Jun 1, 2017
813 813: Increased, Serum creatinine 818: Occurrence, Cytoplasmic vacuolization (Renal tubule) Nov 29, 2016 Dec 3, 2016
814 813: Increased, Serum creatinine 823: Occurrence, Cystic dilatation (renal tubule) Nov 29, 2016 Dec 3, 2016
816 813: Increased, Serum creatinine 824: Occurrence, Cytoplasmic vacuolization (podocyte) Nov 29, 2016 Dec 3, 2016
2582 1972: Increased, Steroidogenic acute regulatory protein (StAR) 1973: Increased, estrogens Feb 26, 2022 Mar 1, 2022
3367 2269: Increased, SREBP2 protein expression 2270: Increased, cholesterol synthesis enzymes Oct 22, 2024 Feb 10, 2025
3388 2269: Increased, SREBP2 protein expression 2276: Increased, PCSK9 protein expression Nov 13, 2024 Feb 13, 2025