Prototypical Stressors

Showing 751 to 775 of 855 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

143	Androstenedione		None
778	amyloid beta		475: Binding of chemicals to ionotropic glutamate receptors leads to impairment of learning and memory via loss of drebrin from dendritic spines of neurons
417	Amphomycin		None
666	Ammonia	Ammonia, CAS-RN: 7664-41-7, DTXSID0023872	None
383	Amlodipine	Amlodipine, CAS-RN: 88150-42-9, DTXSID7022596	2 AOPs 261: L-type calcium channel blockade leading to heart failure via decrease in cardiac contractility 552: Inhibiton of L-Type Calcium Channels leading to heart failure via QT interval prolongation and Torsades de Pointes (TdP)
183	Amlexanox		None
72	Amitrole	Amitrole, CAS-RN: 61-82-5, DTXSID0020076	None
396	Amiodarone, Benzbromarone		None
95	Amiodarone	Amiodarone, CAS-RN: 1951-25-3, DTXSID7022592	2 AOPs 555: Inhibition, Ether-a-go-go (ERG) Voltage-Gated Potassium Channel leading to heart failure 560: Inhibition of Funny current (If) leading to Arrhythmias
493	Aminooxyacetic acid	Aminooxyacetic acid, CAS-RN: 645-88-5, DTXSID50214756	301: Inhibition of Cystathionine Beta synthase leading to impaired the early development of anterior-posterior axis
327	Aminoglycosides		257: Receptor mediated endocytosis and lysosomal overload leading to kidney toxicity
720	Aluminum	Aluminum, CAS-RN: 7429-90-5, DTXSID3040273	None
763	Altered Gravity		None
116	Alpha,Beta-Thujone		None
227	alpha-tocopheryl succinate		None
120	Alpha-endosulfan		None
9	Allyl Alcohol	Allyl alcohol, CAS-RN: 107-18-6, DTXSID8020044	38: Protein Alkylation leading to Liver Fibrosis
697	all-trans-Retinoic acid	all-trans-Retinoic acid, CAS-RN: 302-79-4, DTXSID7021239	None
731	All-trans retionic acid		436: Inhibition of RALDH2 causes reduced all-trans retinoic acid levels, leading to transposition of the great arteries
725	All-trans retinoic acid		615: Suppression of Keap1 cysteine oxidation leading to liver inflammation
826	Aldrin	Aldrin, CAS-RN: 309-00-2, DTXSID8020040	561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
820	Aldicarb		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
333	Albumin	Albumin, CAS-RN: 308060-74-4, DTXSID1040409	257: Receptor mediated endocytosis and lysosomal overload leading to kidney toxicity
61	Aflatoxin B1	Aflatoxin B1, CAS-RN: 1162-65-8, DTXSID9020035	397: Bulky DNA adducts leading to mutations
325	Adefovir dipivoxil	Adefovir dipivoxil, CAS-RN: 142340-99-6, DTXSID5046487	256: Inhibition of mitochondrial DNA polymerase gamma leading to kidney toxicity