Prototypical Stressors

Showing 801 to 825 of 855 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

321	3,5-Dichlorophenol	3,5-Dichlorophenol, CAS-RN: 591-35-5, DTXSID2025006	2 AOPs 245: Reduction in photophosphorylation leading to growth inhibition in aquatic plants 263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
758	3,3′,5,5′ tetrabromobisphenol A		2 AOPs 485: Thyroid hormone antagonism leading to impaired oligodendrocyte maturation during development and subsequent decreased cognition 487: Unknown MIE altering cholesterol metabolism leading to decreased cognition
835	3,3',5,5'-Tetrabromobisphenol A	3,3',5,5'-Tetrabromobisphenol A, CAS-RN: 79-94-7, DTXSID1026081	565: 17β-Hydroxysteroid dehydrogenase 2, inhibition leading to activation, estrogen receptor alpha
277	3,3'		None
278	3,3		None
228	3-aminopropanal		144: Endocytic lysosomal uptake leading to liver fibrosis
201	3-[3-(4'-bromo[1,1'-biphenyl]-4-yl)-3-hydroxy-1-phenylpropyl]-4-hydroxy-2-benzopyrone		187: Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage
87	3-(Difluoromethyl)-1-(4-methoxyphenyl)-5-[4-(methylsulfinyl)phenyl]-1H-pyrazole		None
89	2058-46-0		None
241	20-hydroxyecdysone	20-Hydroxyecdysone, CAS-RN: 5289-74-7, DTXSID5040388	2 AOPs 4: Ecdysone receptor agonism leading to mortality via suppression of Ftz-f1 342: Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade
719	2) Aluminum		None
6	2(3H)-Benzothiazolethione		None
101	2,6-dinitrotoluene	2,6-Dinitrotoluene, CAS-RN: 606-20-2, DTXSID5020528	None
264	2,6-dinitro-p-cresol		152: Interference with thyroid serum binding protein transthyretin and subsequent adverse human neurodevelopmental toxicity
361	2,5-Hexanedione	2,5-Hexanedione, CAS-RN: 110-13-4, DTXSID8030138	None
348	2,4-Dithiobiuret	2,4-Dithiobiuret, CAS-RN: 541-53-7, DTXSID2034968	None
100	2,4-dinitrotoluene	2,4-Dinitrotoluene, CAS-RN: 121-14-2, DTXSID0020529	None
180	2,4-Dinitrophenol	2,4-Dinitrophenol, CAS-RN: 51-28-5, DTXSID0020523	263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
249	2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)		9 AOPs 21: Aryl hydrocarbon receptor activation leading to early life stage mortality, via increased COX-2 455: Aryl hydrocarbon receptor activation leading to early life stage mortality via sox9 repression induced impeded craniofacial development 456: Aryl hydrocarbon receptor activation leading to early life stage mortality via sox9 repression induced cardiovascular toxicity 439: Activation of the AhR leading to metastatic breast cancer 458: AhR activation in the liver leading to Subsequent Adverse Neurodevelopmental Outcomes in Mammals 459: AhR activation in the thyroid leading to Subsequent Adverse Neurodevelopmental Outcomes in Mammals 494: AhR activation leading to liver fibrosis 563: Aryl hydrocarbon Receptor (AHR) activation causes Premature Ovarian Insufficiency via Bax mediated apoptosis 578: AhR activation leading to cancer progression via immunosuppression
413	2,3-Pentanedione	2,3-Pentanedione, CAS-RN: 600-14-6, DTXSID6051435	None
414	2,3-Butanedione	2,3-Butanedione, CAS-RN: 431-03-8, DTXSID6021583	None
74	2,2',4,4'-Tetrahydroxybenzophenone	2,2',4,4'-Tetrahydroxybenzophenone, CAS-RN: 131-55-5, DTXSID5041306	2 AOPs 175: Thyroperoxidase inhibition leading to altered amphibian metamorphosis 152: Interference with thyroid serum binding protein transthyretin and subsequent adverse human neurodevelopmental toxicity
845	2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether	2,2',3,3',4,4',5,5',6,6'-Decabromodiphenyl ether, CAS-RN: 1163-19-5, DTXSID9020376	None
512	2-Methoxyestradiol	2-Methoxyestradiol, CAS-RN: 362-07-2, DTXSID3040938	None
7	2-mercaptobenzothiazole	2-Mercaptobenzothiazole, CAS-RN: 149-30-4, DTXSID1020807	None