Key Event Relationships (KERs)

API

Fulltext search has been disabled for Key Event Relationships (KERs) at this time. If you need this feature, send an email to aopwiki@googlegroups.com

Queries Key Event Relationship (KER) titles
Filter by Upstream Key Event title
Filter by Downstream Key Event title
Filter by AOP title
Clear All Filters

Showing 2701 to 2725 of 3081 KERs

Clear Table Filters
ID Upstream Event Downstream Event Creation Date Last Updated AOPs
764 209: Peptide Oxidation 719: Increase, hepatocellular adenomas and carcinomas Nov 29, 2016 Dec 3, 2016 None
765 209: Peptide Oxidation 768: Increase, Cytotoxicity Nov 29, 2016 Dec 3, 2016
922 209: Peptide Oxidation 177: Increase, Mitochondrial dysfunction Nov 29, 2016 Nov 29, 2016 None
923 209: Peptide Oxidation 87: Release, Cytokine Nov 29, 2016 Dec 3, 2016 None
932 209: Peptide Oxidation 357: Cholestasis, Pathology Nov 29, 2016 Dec 3, 2016
948 209: Peptide Oxidation 926: Oxidation, Glutathione Nov 29, 2016 Nov 29, 2016 None
980 209: Peptide Oxidation 935: Decrease, GTPCH-1 Nov 29, 2016 Sep 28, 2017
992 209: Peptide Oxidation 973: Decrease, AKT/eNOS activity Nov 29, 2016 Oct 16, 2017
1237 209: Peptide Oxidation 1172: Increased activation, Nuclear factor kappa B (NF-kB) Nov 29, 2016 Dec 3, 2016 None
1379 209: Peptide Oxidation 1292: Activation, JNK Feb 15, 2017 Feb 15, 2017
1467 209: Peptide Oxidation 1194: Increase, DNA Damage Apr 15, 2017 Apr 15, 2017 None
1698 209: Peptide Oxidation 927: S-Glutathionylation, eNOS Nov 16, 2017 Nov 20, 2017
2516 1947: Pericyte dysfunction 1913: Endothelial cell dysfunction Oct 28, 2021 Oct 28, 2021 None
395 228: demethylation, PPARg promoter 408: reduction in ovarian granulosa cells, Aromatase (Cyp19a1) Nov 29, 2016 Dec 3, 2016 None
411 228: demethylation, PPARg promoter 54: Up Regulation, CD36 Nov 29, 2016 Nov 29, 2016
487 228: demethylation, PPARg promoter 457: Activation, SREBF1 Nov 29, 2016 Dec 3, 2016
1402 228: demethylation, PPARg promoter 1301: Activation, SREBP-1 Apr 12, 2017 Apr 12, 2017 None
1424 228: demethylation, PPARg promoter 116: Activation, FAS Apr 13, 2017 Apr 13, 2017 None
1608 228: demethylation, PPARg promoter 1028: Activation of specific nuclear receptors, PPAR-gamma activation Jul 24, 2017 Jul 24, 2017
1659 228: demethylation, PPARg promoter 465: Increased, FA Influx Aug 31, 2017 Aug 31, 2017
2988 228: demethylation, PPARg promoter 2165: Activation of PPAR Aug 20, 2023 Aug 20, 2023
1125 1086: persistent, cytotoxicity (pleura or peritoneum) 1087: Increased, inflammation Nov 29, 2016 Dec 3, 2016
3261 1086: persistent, cytotoxicity (pleura or peritoneum) 1392: Increase, Oxidative Stress Jul 3, 2024 Jul 3, 2024
1377 1289: Perturbation of cholesterol 1291: Hepatotoxicity Feb 15, 2017 Feb 15, 2017
3427 2288: Phosphodiesterase (PDE) 2284: Intracellular cAMP Nov 22, 2024 Nov 22, 2024 None