Prototypical Stressors

Showing 301 to 325 of 853 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

21	Domoic acid	L-Domoic acid, CAS-RN: 14277-97-5, DTXSID20274180	None
813	Donepezil		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
285	Doxorubicin	Doxorubicin, CAS-RN: 23214-92-8, DTXSID8021480	None
627	Dummy Stressor		None
621	DX600		319: Binding to ACE2 leading to lung fibrosis
69	Dysidenin		54: Inhibition of Na+/I- symporter (NIS) leads to learning and memory impairment
803	E-4031		2 AOPs 555: Inhibition, Ether-a-go-go (ERG) Voltage-Gated Potassium Channel leading to heart failure 556: Decreased Na/K ATPase activity leading to heart failure
247	Ecdysone		4: Ecdysone receptor agonism leading to mortality via suppression of Ftz-f1
219	Econazole		None
302	EGFR ligand		None
843	Elesclomol		590: Increase of intracellular copper leading to cuproptosis via interference with energy metabolism
83	Emamectin benzoate	Emamectin benzoate, CAS-RN: 155569-91-8, DTXSID0034566	2 AOPs 161: Glutamate-gated chloride channel activation leading to neurotransmission inhibition associated mortality 160: Ionotropic gamma-aminobutyric acid receptor activation mediated neurotransmission inhibition leading to mortality
605	Emodin	Emodin, CAS-RN: 518-82-1, DTXSID5025231	263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
345	Endosulfan	Endosulfan, CAS-RN: 115-29-7, DTXSID1020560	2 AOPs 10: Binding to the picrotoxin site of ionotropic GABA receptors leading to epileptic seizures in adult brain 561: Aromatase induction leading to estrogen receptor alpha activation via increased estradiol
350	Enflurane	Enflurane, CAS-RN: 13838-16-9, DTXSID1020562	260: CYP2E1 activation and formation of protein adducts leading to neurodegeneration
807	Enoximone		558: Phosphodiesterase inhibition leading to heart failure
423	Entacapone	Entacapone, CAS-RN: 130929-57-6, DTXSID5046439	None
407	Epidermal growth factor	Epidermal growth factor, CAS-RN: 62229-50-9, DTXSID5040469	None
615	epigallocathechin gallate		None
796	Epinephrine		554: β-adrenergic receptor agonists leading to arrhythmias.
408	Epothilone A	Epothilone A, CAS-RN: 152044-53-6, DTXSID10332288	None
409	Epothilone B	Epothilone B, CAS-RN: 152044-54-7, DTXSID4046862	None
559	Epoxiconazole	Epoxiconazole, CAS-RN: 133855-98-8, DTXSID1040372	None
700	Escitalopram	Escitalopram, CAS-RN: 128196-01-0, DTXSID8048440	None
105	Esfenvalerate	Esfenvalerate, CAS-RN: 66230-04-4, DTXSID4032667	None