Prototypical Stressors

Showing 676 to 700 of 855 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

338	Carbon nanotubes, Multi-walled carbon nanotubes, single-walled carbon nanotubes, carbon nanofibres		2 AOPs 173: Substance interaction with the pulmonary resident cell membrane components leading to pulmonary fibrosis 409: Frustrated phagocytosis leads to malignant mesothelioma
339	Carbon nanotubes, Multi-walled carbon nanotubes, Single-walled carbon nanotubes, carbon fibres		None
318	Carbon nanotubes		3 AOPs 241: Latent Transforming Growth Factor beta1 activation leads to pulmonary fibrosis 237: Substance interaction with lung resident cell membrane components leading to atherosclerosis 409: Frustrated phagocytosis leads to malignant mesothelioma
740	Carbon black	Carbon black, CAS-RN: 1333-86-4, DTXSID7051216	451: Interaction with lung resident cell membrane components leads to lung cancer
822	Carbofuran		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
545	Carbenoxolone	Carbenoxolone, CAS-RN: 5697-56-3, DTXSID4022733	348: Inhibition of 11β-Hydroxysteroid Dehydrogenase leading to decreased population trajectory
129	Carbendazim	Carbendazim, CAS-RN: 10605-21-7, DTXSID4024729	None
819	Carbaryl		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
92	Carbamazepine	Carbamazepine, CAS-RN: 298-46-4, DTXSID4022731	None
786	Carbamate pesticides		551: Increased Muscarinic M2 Receptor leading to Arrhythmia
595	Captan	Captan, CAS-RN: 133-06-2, DTXSID9020243	360: Chitin synthase 1 inhibition leading to mortality
594	Captafol	Captafol, CAS-RN: 2425-06-1, DTXSID4020242	360: Chitin synthase 1 inhibition leading to mortality
597	Capta		None
691	Candesartan cilexetil	Candesartan cilexetil, CAS-RN: 145040-37-5, DTXSID5020239	None
785	Camptothecin		550: Increased LMNA gene mutation leading to heart failure
841	calcium ionophore		None
380	Calcium channel blockers		261: L-type calcium channel blockade leading to heart failure via decrease in cardiac contractility
456	Cadmium chloride	Cadmium chloride, CAS-RN: 10108-64-2, DTXSID6020226	296: Oxidative DNA damage leading to chromosomal aberrations and mutations
335	Cadmium	Cadmium, CAS-RN: 7440-43-9, DTXSID1023940	10 AOPs 257: Receptor mediated endocytosis and lysosomal overload leading to kidney toxicity 499: Activation of MEK-ERK1/2 leads to deficits in learning and cognition via disrupted neurotransmitter release 500: Activation of MEK-ERK1/2 leads to deficits in learning and cognition via ROS and apoptosis 521: Essential element imbalance leads to reproductive failure via oxidative stress 550: Increased LMNA gene mutation leading to heart failure 552: Inhibiton of L-Type Calcium Channels leading to heart failure via QT interval prolongation and Torsades de Pointes (TdP) 555: Inhibition, Ether-a-go-go (ERG) Voltage-Gated Potassium Channel leading to heart failure 560: Inhibition of Funny current (If) leading to Arrhythmias 615: Suppression of Keap1 cysteine oxidation leading to liver inflammation 638: Co-exposure to microplastics and cadmium leading to progression from NAFLD to liver tumorigenesis
341	Butyrate	Butyrate, CAS-RN: 461-55-2, DTXSID8040432	2 AOPs 212: Histone deacetylase inhibition leading to testicular atrophy 274: Histone deacetylase inhibition leads to impeded craniofacial development
561	Butylparaben	4-Hydroxybenzoic acid butyl ester, CAS-RN: 94-26-8, DTXSID3020209	None
687	Butylate	Butylate, CAS-RN: 2008-41-5, DTXSID7023936	None
568	butyl benzyl phthalate		None
12	Butyl 4-hydroxybenzoate	4-Hydroxybenzoic acid butyl ester, CAS-RN: 94-26-8, DTXSID3020209	None
791	Bupivacaine		553: Inhibition of Voltage-gated sodium channels (Na⁺ channels) leading to heart failure