Prototypical Stressors

Showing 676 to 700 of 871 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

622	cationic polyamidoamine dendrimer (nanoparticle)		319: Binding to ACE2 leading to lung fibrosis
809	Catecholamines		558: Phosphodiesterase inhibition leading to heart failure
194	Carprofen	Carprofen, CAS-RN: 53716-49-7, DTXSID1045871	177: Cyclooxygenase 1 (COX1) inhibition leading to renal failure and mortality
858	Carboplatin	Carboplatin, CAS-RN: 41575-94-4, DTXSID3046742	472: DNA adduct formation leading to kidney failure
601	Carbonyl cyanide-p-trifluoromethoxyphenylhydrazone		263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
602	Carbonyl cyanide m-chlorophenyl hydrazone		263: Uncoupling of oxidative phosphorylation leading to growth inhibition via decreased cell proliferation
13	Carbon tetrachloride	Carbon tetrachloride, CAS-RN: 56-23-5, DTXSID8020250	38: Protein Alkylation leading to Liver Fibrosis
338	Carbon nanotubes, Multi-walled carbon nanotubes, single-walled carbon nanotubes, carbon nanofibres		2 AOPs 173: Substance interaction with the pulmonary resident cell membrane components leading to pulmonary fibrosis 409: Frustrated phagocytosis leads to malignant mesothelioma
339	Carbon nanotubes, Multi-walled carbon nanotubes, Single-walled carbon nanotubes, carbon fibres		None
318	Carbon nanotubes		3 AOPs 241: Latent Transforming Growth Factor beta1 activation leads to pulmonary fibrosis 237: Substance interaction with lung resident cell membrane components leading to atherosclerosis via acute phase response 409: Frustrated phagocytosis leads to malignant mesothelioma
740	Carbon black	Carbon black, CAS-RN: 1333-86-4, DTXSID7051216	451: Interaction with lung resident cell membrane components leads to lung cancer
822	Carbofuran		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
545	Carbenoxolone	Carbenoxolone, CAS-RN: 5697-56-3, DTXSID4022733	348: Inhibition of 11β-Hydroxysteroid Dehydrogenase leading to decreased population trajectory
129	Carbendazim	Carbendazim, CAS-RN: 10605-21-7, DTXSID4024729	None
819	Carbaryl		559: Inhibition of acetylcholinesterase (AChE) leading to arrhythmias
92	Carbamazepine	Carbamazepine, CAS-RN: 298-46-4, DTXSID4022731	None
786	Carbamate pesticides		551: Increased Muscarinic M2 Receptor leading to Arrhythmia
595	Captan	Captan, CAS-RN: 133-06-2, DTXSID9020243	360: Chitin synthase 1 inhibition leading to mortality
594	Captafol	Captafol, CAS-RN: 2425-06-1, DTXSID4020242	360: Chitin synthase 1 inhibition leading to mortality
597	Capta		None
691	Candesartan cilexetil	Candesartan cilexetil, CAS-RN: 145040-37-5, DTXSID5020239	None
785	Camptothecin		550: Increased LMNA gene mutation leading to heart failure
841	calcium ionophore		None
380	Calcium channel blockers		261: L-type calcium channel blockade leading to heart failure via decrease in cardiac contractility
456	Cadmium chloride	Cadmium chloride, CAS-RN: 10108-64-2, DTXSID6020226	296: Oxidative DNA damage leading to chromosomal aberrations and mutations