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ID Title Point of Contact License MIE AO OECD Status OECD Project
492 Glutathione conjugation leading to reproductive dysfunction via oxidative stress Leonardo Vieira All rights reserved
  • Conjugation, GSH
  • decreased, Fertility
593 Redox cycling of a chemical by mitochondria leads to degeneration of nigrostriatal dopaminergic neurons Stefan Schildknecht BY-SA
  • Redox cycling of a chemical by mitochondria
  • Parkinsonian motor deficits
37 PPARα activation leading to hepatocellular adenomas and carcinomas in rodents Chris Corton BY-SA
  • Activation, PPARα
  • Increase, hepatocellular adenomas and carcinomas
Under Development 1.17
622 Calcineurin inhibitor induced nephrotoxicity leading to kidney failure Kate Liang All rights reserved
  • Increased, Kidney Failure
482 Deposition of energy leading to occurrence of bone loss Vinita Chauhan BY-SA
  • Deposition of Energy
  • Occurrence, Bone Loss
WPHA/WNT Endorsed 1.89
17 Binding of electrophilic chemicals to SH(thiol)-group of proteins and /or to seleno-proteins involved in protection against oxidative stress during brain development leads to impairment of learning and memory Marie-Gabrielle Zurich BY-SA
  • Binding, Thiol/seleno-proteins involved in protection against oxidative stress
  • Impairment, Learning and memory
WPHA/WNT Endorsed 1.13
470 Deposition of energy leads to abnormal vascular remodeling Vinita Chauhan BY-SA
  • Deposition of Energy
  • Occurrence, Abnormal Vascular Remodeling
WPHA/WNT Endorsed 1.89
478 Deposition of energy leading to occurrence of cataracts Vinita Chauhan BY-SA
  • Deposition of Energy
  • Occurrence of Cataracts
WPHA/WNT Endorsed 1.89
483 Deposition of Energy Leading to Learning and Memory Impairment Vinita Chauhan BY-SA
  • Deposition of Energy
  • Impairment, Learning and memory
WPHA/WNT Endorsed 1.89
296 Oxidative DNA damage leading to chromosomal aberrations and mutations Carole Yauk BY-SA
  • Increase, Oxidative DNA damage
  • Increase, Mutations
  • Increase, Chromosomal aberrations
WPHA/WNT Endorsed 1.76