AOP-Wiki

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All Key Events

Showing 1651 to 1675 of 1939 Key Events

ID	Title	Event Component Count	Biological Organization	Created At	Last Updated	AOPs

591	Increased, amputations Short Name Increased, amputations	1	Individual	Nov 29, 2016	Dec 3, 2016	94: Sodium channel inhibition leading to congenital malformations
590	N/A, hypoxia Short Name N/A, hypoxia	1	Tissue	Nov 29, 2016	Dec 3, 2016	2 AOPs 94: Sodium channel inhibition leading to congenital malformations 546: Succinate dehydrogenase inactivation leads to cancer through hypoxic-like mechanisms
588	Increased, predation Short Name Increased, predation	1	Population	Nov 29, 2016	Dec 3, 2016	5 AOPs 93: sodium channel inhibition leading to increased predation 91: Sodium channel inhibition leading to reduced survival 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival 98: 5-hydroxytryptamine transporter (5-HTT; SERT) inhibition leading to decreased shelter seeking and increased predation 99: Histamine (H2) receptor antagonism leading to reduced survival
587	Reduced, feeding 1 Short Name Reduced, feeding 1	1	Individual	Nov 29, 2016	Nov 29, 2016	2 AOPs 91: Sodium channel inhibition leading to reduced survival 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival
586	Reduced, swimming speed Short Name Reduced, swimming speed	1	Individual	Nov 29, 2016	Nov 29, 2016	3 AOPs 91: Sodium channel inhibition leading to reduced survival 93: sodium channel inhibition leading to increased predation 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival
585	Decreased, Sodium conductance 1 Short Name Decreased, Sodium conductance 1	1	Cellular	Nov 29, 2016	Sep 16, 2017	4 AOPs 91: Sodium channel inhibition leading to reduced survival 93: sodium channel inhibition leading to increased predation 94: Sodium channel inhibition leading to congenital malformations 95: Ether-a-go-go (ERG) voltage-gated potassium channel inhibition leading to reduced survival
584	Inhibition, sodium channel Short Name Inhibition, sodium channel	2	Molecular	Nov 29, 2016	Sep 16, 2017	5 AOPs 91: Sodium channel inhibition leading to reduced survival 93: sodium channel inhibition leading to increased predation 94: Sodium channel inhibition leading to congenital malformations 197: Sodium channel (Nav1.1) inhibition leading to population decline 553: Inhibition of Voltage-gated sodium channels (Na⁺ channels) leading to heart failure
583	impaired, Thoracic shivering Short Name impaired, Thoracic shivering	0	Individual	Nov 29, 2016	Dec 3, 2016	None
580	Reduced, Antiseptic incorporated in food Short Name	0	Population	Nov 29, 2016	Dec 3, 2016	86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure
579	Decreased, Hydrogen peroxide production Short Name Decreased, Hydrogen peroxide production	1	Molecular	Nov 29, 2016	Sep 16, 2017	86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure
578	Decreased, Glucose oxidase enzyme activity Short Name	1	Molecular	Nov 29, 2016	Sep 16, 2017	86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure
577	impaired, Development Short Name impaired, Development	1	Individual	Nov 29, 2016	Dec 3, 2016	84: Suppression of immune system contributes to impaired development and leads to colony loss/failure
576	Increased, Viral susceptibility Short Name Increased, Viral susceptibility	1	Individual	Nov 29, 2016	Dec 3, 2016	2 AOPs 84: Suppression of immune system contributes to impaired development and leads to colony loss/failure 85: Suppression of immune system contributes to abnormal foraging and leads to colony loss/failure
574	Increased, Appetite and hunger Short Name Increased, Appetite and hunger	1	Individual	Nov 29, 2016	Dec 3, 2016	81: Increased metabolic stress contributes to abnormal foraging and leads to colony loss/failure
573	Increase, Energetic demands and therefore metabolic stress Short Name	2	Individual	Nov 29, 2016	Dec 3, 2016	81: Increased metabolic stress contributes to abnormal foraging and leads to colony loss/failure
572	Decrease, Number of worker bees Short Name Decrease, Number of worker bees	1	Population	Nov 29, 2016	Dec 3, 2016	4 AOPs 80: Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure 84: Suppression of immune system contributes to impaired development and leads to colony loss/failure 85: Suppression of immune system contributes to abnormal foraging and leads to colony loss/failure 81: Increased metabolic stress contributes to abnormal foraging and leads to colony loss/failure
571	Accelerated, Aging Short Name Accelerated, Aging	1	Individual	Nov 29, 2016	Dec 3, 2016	80: Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure
570	Accumulation, Damaged mitochondrial DNA Short Name Accumulation, Damaged mitochondrial DNA	1	Cellular	Nov 29, 2016	Sep 16, 2017	80: Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure
568	impaired, Hive thermoregulation Short Name impaired, Hive thermoregulation	1	Population	Nov 29, 2016	Dec 3, 2016	3 AOPs 80: Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure 84: Suppression of immune system contributes to impaired development and leads to colony loss/failure 79: Nicotinic acetylcholine receptor activation contributes to impaired hive thermoregulation and leads to colony loss/failure
566	impaired, Larval development Short Name impaired, Larval development	1	Population	Nov 29, 2016	Dec 3, 2016	5 AOPs 78: Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1 82: Abnormal role change in worker caste contributes to reduced brood care and leads to colony loss/failure 86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure 90: Nicotinic acetylcholine receptor activation contributes to abnormal roll change within the worker bee caste leading to colony loss/failure 2 564: DBDPE-induced inhibition of mitochondrial complex Ⅰ leading to population decline via neurotoxicity and metabotoxicity.
565	Reduced, Brood care Short Name Reduced, Brood care	2	Population	Nov 29, 2016	Dec 3, 2016	3 AOPs 78: Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1 82: Abnormal role change in worker caste contributes to reduced brood care and leads to colony loss/failure 90: Nicotinic acetylcholine receptor activation contributes to abnormal roll change within the worker bee caste leading to colony loss/failure 2
564	Abnormal, Roll change within caste Short Name Abnormal, Roll change within caste	0	Population	Nov 29, 2016	Dec 3, 2016	4 AOPs 78: Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1 82: Abnormal role change in worker caste contributes to reduced brood care and leads to colony loss/failure 86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure 90: Nicotinic acetylcholine receptor activation contributes to abnormal roll change within the worker bee caste leading to colony loss/failure 2
563	Death/Failure, Colony Short Name Death/Failure, Colony	1	Population	Nov 29, 2016	Jun 7, 2018	21 AOPs 78: Nicotinic acetylcholine receptor activation contributes to abnormal role change within the worker bee caste leading to colony death failure 1 79: Nicotinic acetylcholine receptor activation contributes to impaired hive thermoregulation and leads to colony loss/failure 80: Nicotinic acetylcholine receptor activation contributes to accumulation of damaged mitochondrial DNA and leads to colony loss/failure 82: Abnormal role change in worker caste contributes to reduced brood care and leads to colony loss/failure 84: Suppression of immune system contributes to impaired development and leads to colony loss/failure 85: Suppression of immune system contributes to abnormal foraging and leads to colony loss/failure 86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure 87: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure 88: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure via abnormal role change within caste 89: Nicotinic acetylcholine receptor activation followed by desensitization contributes to abnormal foraging and directly leads to colony loss/failure 90: Nicotinic acetylcholine receptor activation contributes to abnormal roll change within the worker bee caste leading to colony loss/failure 2 77: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony death/failure 1 81: Increased metabolic stress contributes to abnormal foraging and leads to colony loss/failure 178: Nicotinic acetylcholine receptor activation contributes to mitochondrial dysfunction and leads to colony loss/failure 179: Varroa mite infestation increases virus levels leading to colony loss/failure 180: Varroa mite infestation contributes to abnormal foraging leading to colony loss/failure 181: Weather event contributes to colony loss/failure 182: Weather event contributes abnormal foraging leading to colony loss/failure 183: Nosema infection increases energetic demands leading to colony loss/failure 184: Nosema infection causes abnormal role change that leads to colony loss/failure 185: Queen egg-laying decrease leads to colony loss/failure
561	Reduced, Food storage Short Name Reduced, Food storage	1	Population	Nov 29, 2016	Dec 3, 2016	86: Decrease Glucose oxidase activity contributes to reduction of antiseptic in food and leads to colony loss/failure
560	Abnormal, Foraging activity and behavior Short Name	1	Individual	Nov 29, 2016	Jun 7, 2018	9 AOPs 77: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony death/failure 1 81: Increased metabolic stress contributes to abnormal foraging and leads to colony loss/failure 85: Suppression of immune system contributes to abnormal foraging and leads to colony loss/failure 87: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure 88: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure via abnormal role change within caste 89: Nicotinic acetylcholine receptor activation followed by desensitization contributes to abnormal foraging and directly leads to colony loss/failure 180: Varroa mite infestation contributes to abnormal foraging leading to colony loss/failure 182: Weather event contributes abnormal foraging leading to colony loss/failure 183: Nosema infection increases energetic demands leading to colony loss/failure