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All KERs

Showing 3076 to 3081 of 3081 KERs

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ID	Upstream Event	Downstream Event	Creation Date	Last Updated	AOPs

2693	2032: Viable offspring, decreased	360: Decrease, Population growth rate	Jul 18, 2022	Jul 18, 2022	None
1639	1465: Weak collagen matrix	1466: Notochord malformation	Aug 3, 2017	Aug 3, 2017	1 AOP 242: Inhibition of lysyl oxidase leading to enhanced chronic fish toxicity
2757	2062: Weak, Procuticle protection	2063: Decrease, New cuticle secretion	Aug 28, 2022	Aug 28, 2022	1 AOP 467: Knickkopf leading to mortality
1145	1107: Weakened, Colony	563: Death/Failure, Colony	Nov 29, 2016	Dec 3, 2016	13 AOPs 77: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony death/failure 1 87: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure 88: Nicotinic acetylcholine receptor activation contributes to abnormal foraging and leads to colony loss/failure via abnormal role change within caste 89: Nicotinic acetylcholine receptor activation followed by desensitization contributes to abnormal foraging and directly leads to colony loss/failure 79: Nicotinic acetylcholine receptor activation contributes to impaired hive thermoregulation and leads to colony loss/failure 178: Nicotinic acetylcholine receptor activation contributes to mitochondrial dysfunction and leads to colony loss/failure 179: Varroa mite infestation increases virus levels leading to colony loss/failure 180: Varroa mite infestation contributes to abnormal foraging leading to colony loss/failure 181: Weather event contributes to colony loss/failure 182: Weather event contributes abnormal foraging leading to colony loss/failure 183: Nosema infection increases energetic demands leading to colony loss/failure 184: Nosema infection causes abnormal role change that leads to colony loss/failure 185: Queen egg-laying decrease leads to colony loss/failure
1924	1645: Wnt ligand stimulation	1646: Frizzled activation	May 29, 2019	May 29, 2019	None
1927	1648: β-catenin activation	1649: Snail, Zeb, Twist activation	May 29, 2019	May 29, 2019	None