| 3606 |
1560: Cell differentiation, altered |
1068: Endometrial squamous metaplasia, Increase |
Aug 21, 2025 |
Aug 28, 2025 |
None
|
| 3609 |
1560: Cell differentiation, altered |
772: Increase, Hyperplasia (glandular epithelial cells of endometrium) |
Aug 26, 2025 |
Aug 29, 2025 |
None
|
| 995 |
853: Changes/Inhibition, Cellular Homeostasis and Apoptosis |
139: N/A, Hepatotoxicity, Hepatopathy, including a constellation of observable effects |
Nov 29, 2016 |
Dec 2, 2016 |
1 AOP
|
| 1613 |
1454: chronic high fat diet |
1450: decreased dopamine |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 2069 |
1753: Chronic ROS |
1754: Increase, porcupine-induced Wnt secretion and Wnt signaling activation |
Mar 23, 2020 |
Jun 12, 2025 |
None
|
| 1314 |
1251: Chronic, Mucus hypersecretion |
1250: Decreased lung function |
Nov 29, 2016 |
Aug 30, 2021 |
None
|
| 2442 |
1908: CBF, Decreased |
1909: MCC, Decreased |
Jul 19, 2021 |
Mar 24, 2023 |
3 AOPs
|
| 550 |
491: Clonal Expansion/Cell Proliferation, to form Altered Hepatic Foci (AHF) |
378: Tumorigenesis, Hepatocellular carcinoma |
Nov 29, 2016 |
Nov 29, 2016 |
1 AOP
|
| 2290 |
1845: Coagulation |
1846: Thrombosis and DIC |
Mar 25, 2021 |
Jun 23, 2024 |
1 AOP
|
| 2313 |
1845: Coagulation |
1392: Increase, Oxidative Stress |
Apr 8, 2021 |
Apr 8, 2021 |
None
|
| 2360 |
1845: Coagulation |
1869: Diminished Protective Response to ROS |
Apr 20, 2021 |
Jun 21, 2024 |
1 AOP
|
| 2801 |
2075: Hemocyanin Bohr effect decrease |
2077: behavioral change leading to possible reduced feeding opportunity |
Nov 16, 2022 |
Nov 16, 2022 |
1 AOP
|
| 1359 |
1275: Collagen Deposition |
1276: Lung fibrosis |
Feb 15, 2017 |
Feb 15, 2017 |
1 AOP
|
| 1628 |
1275: Collagen Deposition |
68: Increase, Collagen accumulation |
Jul 26, 2017 |
Jul 26, 2017 |
None
|
| 1804 |
1558: Reduced collagen production |
1559: Smaller and morphologically distorted facial cartilage structures |
Dec 20, 2018 |
Dec 20, 2018 |
1 AOP
|
| 2877 |
2131: Conjugation, GSH |
130: Depletion, GSH |
Apr 5, 2023 |
Sep 14, 2023 |
1 AOP
|
| 2276 |
1835: Cortisol and 11β-(OH) testosterone decreased |
1836: Decreased plasma Cortisol level |
Feb 9, 2021 |
Feb 9, 2021 |
1 AOP
|
| 2277 |
1835: Cortisol and 11β-(OH) testosterone decreased |
1756: Decreased, 11KT |
Feb 9, 2021 |
Feb 9, 2021 |
1 AOP
|
| 376 |
396: Covalent Binding, Protein |
397: Response, Keratinocytes |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 377 |
396: Covalent Binding, Protein |
398: Activation, Dendritic Cells |
Nov 29, 2016 |
Nov 5, 2020 |
2 AOPs
|
| 833 |
396: Covalent Binding, Protein |
826: Activation, Keratinocytes |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 2202 |
396: Covalent Binding, Protein |
151: Activation, Inflammatory cytokines, chemokines, cytoprotective gene pathways |
Nov 5, 2020 |
Feb 11, 2021 |
None
|
| 2649 |
396: Covalent Binding, Protein |
1496: Increased proinflammatory mediators |
Apr 28, 2022 |
Sep 8, 2022 |
1 AOP
|
| 2650 |
396: Covalent Binding, Protein |
313: Increase, Allergic Respiratory Hypersensitivity Response |
Apr 28, 2022 |
Aug 1, 2022 |
1 AOP
|
| 3539 |
2326: CTL cytotoxicity |
2325: Decreased number of LT CD8+ cells |
May 22, 2025 |
May 22, 2025 |
None
|