Key Event Relationships (KERs)

API

Fulltext search has been disabled for Key Event Relationships (KERs) at this time. If you need this feature, send an email to aopwiki@googlegroups.com

Queries Key Event Relationship (KER) titles
Filter by Upstream Key Event title
Filter by Downstream Key Event title
Filter by AOP title
Clear All Filters

Showing 2276 to 2300 of 3081 KERs

Clear Table Filters
ID Upstream Event Downstream Event Creation Date Last Updated AOPs
2512 1666: dysfunction of microcirculation 1750: Increased inflammatory immune responses Oct 28, 2021 Oct 28, 2021 None
1221 1167: induced, parturition 1141: Decreased, Reproductive Success Nov 29, 2016 Dec 3, 2016 None
2021 1711: Induction of GATA3 expression 1712: Increase of Th2 cells producing IL-4 Dec 29, 2019 Aug 14, 2020
2538 1959: Induction of hERG trafficking defects 1960: Inhibition of Ikr Dec 13, 2021 Dec 13, 2021 None
1630 1459: Cell damage sensing 1455: Sustained inflammatory cytokine release Jul 26, 2017 Jul 26, 2017 None
1632 1459: Cell damage sensing 1032: Increased, secretion of local growth factors Jul 26, 2017 Jul 26, 2017 None
70 60: Induction, Chitin degradation and resorption 238: Induction, Pre-mature molting Nov 29, 2016 Dec 3, 2016 None
868 850: Induction, CYP1A2/CYP1A5 844: Oxidation, Uroporphyrinogen Nov 29, 2016 May 31, 2018
3275 850: Induction, CYP1A2/CYP1A5 1392: Increase, Oxidative Stress Jul 4, 2024 Jul 4, 2024
1262 1206: Induction, Doublesex1 gene 1209: Induction, Male reproductive tract Nov 29, 2016 Dec 3, 2016
386 145: Induction, IKB inhibitory protein 202: Inhibition, Nuclear factor kappa B (NF-kB) Nov 29, 2016 Dec 3, 2016
170 164: Induction, Liver “Dysfunctional” Changes by CGA 330050 147: Inhibition, Inducible Nitric Oxide Synthase by Metabolite CGA 265307 Nov 29, 2016 Dec 3, 2016
1263 1209: Induction, Male reproductive tract 1208: Increased, Male offspring Nov 29, 2016 Dec 3, 2016
859 838: Induction, Microvesicular fat 840: Formation, Liver fibrosis Nov 29, 2016 Dec 3, 2016
1518 1394: Sustained proliferation 1395: Liver Cancer May 30, 2017 Oct 9, 2020
1059 1019: Induction, pharyngeal muscle paralysis 1016: Inhibition, Feeding Nov 29, 2016 Dec 3, 2016
261 238: Induction, Pre-mature molting 328: Decrease, Fecundity Nov 29, 2016 Dec 3, 2016 None
262 238: Induction, Pre-mature molting 350: Increase, Mortality Nov 29, 2016 Dec 3, 2016 None
263 238: Induction, Pre-mature molting 351: Increased Mortality Nov 29, 2016 Dec 3, 2016 None
1050 1014: Induction, Somatic muscle paralysis 351: Increased Mortality Nov 29, 2016 Dec 3, 2016
1055 1014: Induction, Somatic muscle paralysis 1016: Inhibition, Feeding Nov 29, 2016 Dec 3, 2016
3089 1014: Induction, Somatic muscle paralysis 1015: Increased, Neuronal synaptic inhibition Oct 17, 2023 Oct 17, 2023
298 269: Induction, Sustained Cell Proliferation 347: Formation, Liver tumor Nov 29, 2016 Dec 3, 2016
299 270: Induction, Sustained Hepatotoxicity 269: Induction, Sustained Cell Proliferation Nov 29, 2016 Dec 3, 2016
2235 295: Induction, Upregulation of glucuronyltransferase activity 401: Increase, Biliary excretion TH glucuronide Dec 9, 2020 Dec 9, 2020 None