| 2801 |
2075: Hemocyanin Bohr effect decrease |
2077: behavioral change leading to possible reduced feeding opportunity |
Nov 16, 2022 |
Nov 16, 2022 |
1 AOP
|
| 3748 |
2414: COL3A1 Signaling Pathway |
1195: modulation, Extracellular Matrix Composition |
Mar 25, 2026 |
Jun 4, 2026 |
1 AOP
|
| 1359 |
1275: Collagen Deposition |
1276: Lung fibrosis |
Feb 15, 2017 |
Feb 15, 2017 |
1 AOP
|
| 1628 |
1275: Collagen Deposition |
68: Increase, Collagen accumulation |
Jul 26, 2017 |
Jul 26, 2017 |
None
|
| 1804 |
1558: Reduced collagen production |
1559: Smaller and morphologically distorted facial cartilage structures |
Dec 20, 2018 |
Dec 20, 2018 |
1 AOP
|
| 2877 |
2131: Conjugation, GSH |
130: Depletion, GSH |
Apr 5, 2023 |
Sep 14, 2023 |
1 AOP
|
| 2276 |
1835: Cortisol and 11β-(OH) testosterone decreased |
1836: Decreased plasma Cortisol level |
Feb 9, 2021 |
Feb 9, 2021 |
1 AOP
|
| 2277 |
1835: Cortisol and 11β-(OH) testosterone decreased |
1756: Decreased, 11KT |
Feb 9, 2021 |
Feb 9, 2021 |
1 AOP
|
| 376 |
396: Covalent Binding, Protein |
397: Response, Keratinocytes |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 377 |
396: Covalent Binding, Protein |
398: Activation, Dendritic Cells |
Nov 29, 2016 |
Nov 5, 2020 |
2 AOPs
|
| 833 |
396: Covalent Binding, Protein |
826: Activation, Keratinocytes |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 2202 |
396: Covalent Binding, Protein |
151: Activation, Inflammatory cytokines, chemokines, cytoprotective gene pathways |
Nov 5, 2020 |
Feb 11, 2021 |
None
|
| 2649 |
396: Covalent Binding, Protein |
1496: Increased proinflammatory mediators |
Apr 28, 2022 |
Sep 8, 2022 |
1 AOP
|
| 2650 |
396: Covalent Binding, Protein |
313: Increase, Allergic Respiratory Hypersensitivity Response |
Apr 28, 2022 |
Aug 1, 2022 |
1 AOP
|
| 3539 |
2326: CTL cytotoxicity |
2325: Decreased number of LT CD8+ cells |
May 22, 2025 |
May 22, 2025 |
None
|
| 3541 |
2326: CTL cytotoxicity |
1971: tumor growth |
Jun 10, 2025 |
Jun 10, 2025 |
1 AOP
|
| 3309 |
1508: CYP2E1 Activation |
1392: Increase, Oxidative Stress |
Jul 23, 2024 |
Jul 23, 2024 |
1 AOP
|
| 1493 |
1386: CYP7B activity, inhibition |
1387: 7α-hydroxypregnenolone synthesis in the brain, decreased |
May 2, 2017 |
May 17, 2017 |
2 AOPs
|
| 1494 |
1386: CYP7B activity, inhibition |
1389: Locomotor activity, decreased |
May 2, 2017 |
May 17, 2017 |
1 AOP
|
| 2440 |
1906: CFTR Function, Decreased |
1907: ASL Height, Decreased |
Jul 19, 2021 |
Sep 7, 2021 |
1 AOP
|
| 839 |
829: Damage, Lipid bilayer |
833: Occurrence, Cytoplasmic vacuolization (hepatocyte) |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 840 |
829: Damage, Lipid bilayer |
835: Occurrence, Ballooning degeneration (hepatocyte) |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 841 |
829: Damage, Lipid bilayer |
836: Occurrence, Cytoplasmic vacuolization (Bile duct cell) |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 842 |
829: Damage, Lipid bilayer |
837: Occurrence, Cytoplasmic vacuolization (kupffer cell) |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 277 |
250: Damaging, Red blood cells; hemolysis |
161: Increase, Liver and splenic hemosiderosis |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|