Prototypical Stressors

Showing 701 to 725 of 853 Prototypical Stressors

ID	Prototypical Stressor Name	Associated Chemical(s): Name, CAS-RN, DTXSID	Associated AOPs

677	Serum	Serum, CAS-RN: NOCAS, DTXSID2041123	None
354	Sevoflurane	Sevoflurane, CAS-RN: 28523-86-6, DTXSID8046614	260: CYP2E1 activation and formation of protein adducts leading to neurodegeneration
674	Sex hormone		None
254	Silica nanoparticles		2 AOPs 209: Perturbation of cholesterol and glutathione homeostasis leading to hepatotoxicity: Integrated multi-OMICS approach for building AOP 481: AOPs of amorphous silica nanoparticles: ROS-mediated oxidative stress increased respiratory dysfunction and diseases.
711	Silver	Silver, CAS-RN: 7440-22-4, DTXSID4024305	None
252	Silver nanoparticles		207: NADPH oxidase and P38 MAPK activation leading to reproductive failure in Caenorhabditis elegans
555	Simvastatin	Simvastatin, CAS-RN: 79902-63-9, DTXSID0023581	None
444	Sinefungin	Sinefungin, CAS-RN: 58944-73-3, DTXSID10207689	2 AOPs 290: Mitochondrial ATP synthase antagonism leading to growth inhibition (1) 291: Mitochondrial ATP synthase antagonism leading to growth inhibition (2)
305	Single walled carbon nanotubes		409: Frustrated phagocytosis leads to malignant mesothelioma
221	Small molecules: ITB3, ITB4, ITB5, ITB9		None
91	Sodium (4-fluoro-2-{[(1S)-1-phenylpropyl]carbamoyl}phenyl)(quinolin-8-ylsulfonyl)azanide		None
458	Sodium arsenite	Sodium arsenite, CAS-RN: 7784-46-5, DTXSID5020104	None
777	Sodium L-glutamate	Sodium L-glutamate, CAS-RN: 142-47-2, DTXSID9020906	475: Binding of chemicals to ionotropic glutamate receptors leads to impairment of learning and memory via loss of drebrin from dendritic spines of neurons
307	Sodium metam		242: Inhibition of lysyl oxidase leading to enhanced chronic fish toxicity
491	soluble IL-1R (Rilonacept)		277: Impaired IL-1R1 signaling leading to Impaired T-Cell Dependent Antibody Response
800	Sotalol		555: Inhibition, Ether-a-go-go (ERG) Voltage-Gated Potassium Channel leading to heart failure
52	Spironolactone	Spironolactone, CAS-RN: 52-01-7, DTXSID6034186	None
270	SSRI (Selective serotonin reuptake inhibitor)		3 AOPs 214: Network of SSRIs (selective serotonin reuptake inhibitors) 226: SSRI (Selective serotonin reuptake inhibitor) to hypertension 568: Inhibition, 5-hydroxytryptamine transporter (5-HTT; SERT) leads to Inhibition, Feeding
643	Staurosporine	Staurosporine, CAS-RN: 62996-74-1, DTXSID6041131	399: Inhibition of Fyna leading to increased mortality via decreased eye size (Microphthalmos)
550	Streptozocin		319: Binding to ACE2 leading to lung fibrosis
346	Stressor:147 Dibenzo-p-dioxin		None
283	Stressor:159 dibenzofuran		None
607	Stressor:205 pirinixic acid (WY-14,643)		None
696	Stressor:282 Ketoconazole		None
581	Stressor:286 Tebuconazole		None