| 1125 |
1086: persistent, cytotoxicity (pleura or peritoneum) |
1087: Increased, inflammation |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 3261 |
1086: persistent, cytotoxicity (pleura or peritoneum) |
1392: Increase, Oxidative Stress |
Jul 3, 2024 |
Jul 3, 2024 |
1 AOP
|
| 1377 |
1289: Perturbation of cholesterol |
1291: Hepatotoxicity |
Feb 15, 2017 |
Feb 15, 2017 |
1 AOP
|
| 3427 |
2288: Phosphodiesterase (PDE) |
2284: Intracellular cAMP |
Nov 22, 2024 |
Nov 22, 2024 |
None
|
| 3445 |
2288: Phosphodiesterase (PDE) |
693: Increased, cyclic adenosine monophosphate |
Nov 26, 2024 |
Nov 26, 2024 |
1 AOP
|
| 2151 |
1794: Pin-1 activation |
1795: TGFbeta expression |
Jul 9, 2020 |
Jul 9, 2020 |
1 AOP
|
| 3438 |
2294: Plasma E2, increased |
2251: Increased E2 availability |
Nov 22, 2024 |
Nov 22, 2024 |
1 AOP
|
| 3718 |
2294: Plasma E2, increased |
2306: Persistent vaginal cornification |
Jan 29, 2026 |
Feb 3, 2026 |
1 AOP
|
| 3746 |
2294: Plasma E2, increased |
2413: Increased, uterine weight |
Mar 13, 2026 |
Mar 13, 2026 |
1 AOP
|
| 3761 |
2294: Plasma E2, increased |
2415: Precocious puberty |
Mar 26, 2026 |
Mar 26, 2026 |
1 AOP
|
| 3769 |
2294: Plasma E2, increased |
1075: prolonged, estrus cycle |
Apr 6, 2026 |
Apr 6, 2026 |
1 AOP
|
| 2456 |
1914: Platelet activation, Increased |
1857: Platelet-neutrophil interactions, Increased |
Aug 4, 2021 |
Aug 4, 2021 |
1 AOP
|
| 2458 |
1857: Platelet-neutrophil interactions, Increased |
1916: Thromboinflammation, Increased |
Aug 4, 2021 |
Aug 4, 2021 |
1 AOP
|
| 2607 |
1979: Premature differentiation |
1978: Microcephaly |
Mar 21, 2022 |
Mar 21, 2022 |
None
|
| 3107 |
1979: Premature differentiation |
2200: decline, neural progenitor cells |
Jan 10, 2024 |
Jan 10, 2024 |
1 AOP
|
| 1211 |
1146: premature, Spawning |
1164: Increased, Population |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 1222 |
1146: premature, Spawning |
1141: Decreased, Reproductive Success |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 1179 |
1144: premature, spawning 1 |
1141: Decreased, Reproductive Success |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 3708 |
2400: Preputial epithelial morphogenesis, disrupted |
2401: Male PPS, failed/delayed |
Dec 16, 2025 |
Dec 16, 2025 |
1 AOP
|
| 1283 |
1234: Production of nerve growth factor , Epithelial irritation |
1222: SP (Substance P) release, Local increase of SP |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 1358 |
1274: Production of α-smooth muscle actin |
1276: Lung fibrosis |
Feb 15, 2017 |
Feb 15, 2017 |
None
|
| 93 |
77: Production, Critical Metabolites (CGA 330050 and CGA 265307) |
164: Induction, Liver “Dysfunctional” Changes by CGA 330050 |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 332 |
302: Production, VEGF-A |
301: Binding, VEGF-A |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 333 |
302: Production, VEGF-A |
304: Decreased, VegfR2 |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 69 |
57: Proliferation, Cell proliferation in the absence of cytotoxicity |
142: Hyperplasia, Hyperplasia |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|