| 3060 |
2197: Decrease, sox10 |
352: N/A, Neurodegeneration |
Oct 17, 2023 |
Oct 17, 2023 |
1 AOP
|
| 2685 |
2020: Decrease, sox9 expression |
1559: Smaller and morphologically distorted facial cartilage structures |
Jun 30, 2022 |
Oct 20, 2022 |
1 AOP
|
| 2691 |
2020: Decrease, sox9 expression |
317: Altered, Cardiovascular development/function |
Jun 30, 2022 |
Oct 20, 2022 |
1 AOP
|
| 436 |
266: Decrease, Steroidogenic acute regulatory protein (STAR) |
447: Reduction, Cholesterol transport in mitochondria |
Nov 29, 2016 |
Apr 8, 2025 |
1 AOP
|
| 1547 |
1382: Decrease, surfactant |
1405: Reduced, mucosal defense |
Jun 2, 2017 |
Jun 2, 2017 |
1 AOP
|
| 1888 |
1622: Decrease, Transgenerational DNA methylation |
1621: Increase, Gene expression |
Apr 22, 2019 |
Apr 22, 2019 |
None
|
| 399 |
289: Decrease, Translocator protein (TSPO) |
413: Reduction, Testosterone synthesis in Leydig cells |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 437 |
289: Decrease, Translocator protein (TSPO) |
447: Reduction, Cholesterol transport in mitochondria |
Nov 29, 2016 |
Dec 2, 2016 |
1 AOP
|
| 2098 |
1772: Decrease, TAG |
1771: Decrease, ATP pool |
Apr 30, 2020 |
Apr 30, 2020 |
1 AOP
|
| 2744 |
2051: Decrease, Tyrosine |
2052: Decrease, dopa decarboxylase |
Aug 28, 2022 |
Aug 28, 2022 |
1 AOP
|
| 3678 |
2384: Decrease, Vascular integrity |
2383: Increase, Hemopericardium |
Oct 30, 2025 |
Oct 30, 2025 |
2 AOPs
|
| 3216 |
450: Decrease, VLDL export capacity |
459: Increase, Liver steatosis |
May 9, 2024 |
May 9, 2024 |
1 AOP
|
| 3515 |
2318: Decreased 3βHSD activity |
1611: Reduction, androstenedione |
Apr 8, 2025 |
Apr 8, 2025 |
None
|
| 3516 |
2318: Decreased 3βHSD activity |
1693: Decreased, Progesterone levels |
Apr 8, 2025 |
Apr 8, 2025 |
None
|
| 3497 |
2309: FAM50B/PTCHD3 methylation |
2310: FAM50B/PTCHD3 expression |
Mar 2, 2025 |
Mar 2, 2025 |
1 AOP
|
| 3502 |
2309: FAM50B/PTCHD3 methylation |
2121: decreased, IQ |
Mar 2, 2025 |
Mar 2, 2025 |
1 AOP
|
| 1618 |
1452: decreased DNA methylation of tyrosine hydroxylase |
1447: obesity |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 1620 |
1452: decreased DNA methylation of tyrosine hydroxylase |
1450: decreased dopamine |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 1614 |
1450: decreased dopamine |
1451: decreased reward |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 2700 |
2026: decrease folate |
1561: Neural tube defects |
Jul 19, 2022 |
Jul 19, 2022 |
1 AOP
|
| 1814 |
1571: Decreased IL-1 production |
1572: Impaired IL-1 signaling |
Dec 25, 2018 |
Jun 25, 2019 |
None
|
| 1824 |
1571: Decreased IL-1 production |
1573: Suppressed MyD88 |
Jan 6, 2019 |
Jan 6, 2019 |
None
|
| 1619 |
1453: decreased methylation of dopamine transporter promoter |
1447: obesity |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 1621 |
1453: decreased methylation of dopamine transporter promoter |
1450: decreased dopamine |
Jul 24, 2017 |
Jul 24, 2017 |
1 AOP
|
| 1811 |
1562: Decreased Na/K ATPase activity |
1563: Decreased proximal tubular vectorial transport |
Dec 20, 2018 |
Dec 20, 2018 |
1 AOP
|