AOPs

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Showing 426 to 450 of 588 AOPs

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ID Title Point of Contact License MIE AO OECD Status OECD Project
197 Sodium channel (Nav1.1) inhibition leading to population decline Kellie Fay BY-SA 584: Inhibition, sodium channel None
196 Volatile Organic Chemicals Activate TRPA1 Receptor to Induce Sensory Pulmonary Irritation Jeanelle Martinez BY-SA 1215: TRPA1 activation, TRPA1 Receptor
195 5-hydroxytryptamine transporter (5-HTT) inhibition leading to population increase Kellie Fay BY-SA 619: Inhibition, 5-hydroxytryptamine transporter (5-HTT; SERT) 1164: Increased, Population
194 Hepatic nuclear receptor activation leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 1157: Activation, Hepatic nuclear receptor(s) 1101: Altered, Amphibian metamorphosis
193 Dual oxidase (DUOX) inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 1156: Inhibition, Dual oxidase 1101: Altered, Amphibian metamorphosis
192 Pendrin inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 1155: Inhibition, Pendrin 1101: Altered, Amphibian metamorphosis
191 Type III iodotyrosine deiodinase (DIO3) inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 1153: Inhibition, Deiodinase 3 1101: Altered, Amphibian metamorphosis
190 Type II iodothyronine deiodinase (DIO2) inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 1002: Inhibition, Deiodinase 2 1101: Altered, Amphibian metamorphosis
189 Type I iodothyronine deiodinase (DIO1) inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 1009: Inhibition, Deiodinase 1 1101: Altered, Amphibian metamorphosis
188 Iodotyrosine deiodinase (IYD) inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 1152: Inhibition, Iodotyrosine deiodinase (IYD) 1101: Altered, Amphibian metamorphosis
187 Anticoagulant rodenticide inhibition of vitamin K epoxide reductase resulting coagulopathy and hemorrhage Undefined BY-SA 1136: Impaired recruitment , Population trajectory Under Development 1.31
186 unknown MIE leading to renal failure and mortality Kellie Fay BY-SA 1114: Unknown, MIE 351: Increased Mortality
185 Queen egg-laying decrease leads to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
184 Nosema infection causes abnormal role change that leads to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
183 Nosema infection increases energetic demands leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
182 Weather event contributes abnormal foraging leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
181 Weather event contributes to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
180 Varroa mite infestation contributes to abnormal foraging leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
179 Varroa mite infestation increases virus levels leading to colony loss/failure Carlie LaLone BY-SA None 563: Death/Failure, Colony
178 Nicotinic acetylcholine receptor activation contributes to mitochondrial dysfunction and leads to colony loss/failure Carlie LaLone BY-SA 559: Activation, Nicotinic acetylcholine receptor 563: Death/Failure, Colony
177 Cyclooxygenase 1 (COX1) inhibition leading to renal failure and mortality Kellie Fay BY-SA 1103: Inhibition, Cyclooxygenase 1 activity
176 Sodium Iodide Symporter (NIS) Inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 424: Inhibition, Na+/I- symporter (NIS) 1101: Altered, Amphibian metamorphosis
175 Thyroperoxidase inhibition leading to altered amphibian metamorphosis Jonathan Haselman BY-SA 279: Thyroperoxidase, Inhibition 1101: Altered, Amphibian metamorphosis
173 Substance interaction with the pulmonary resident cell membrane components leading to pulmonary fibrosis Sabina Halappanavar BY-SA 1495: Substance interaction with the lung resident cell membrane components 1458: Pulmonary fibrosis WPHA/WNT Endorsed 1.32
171 Chronic cytotoxicity of the serous membrane leading to pleural/peritoneal mesotheliomas in the rat. Charles Wood BY-SA None 1090: Increased, mesotheliomas