Key Event Relationships (KERs)

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Showing 1426 to 1450 of 3081 KERs

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ID Upstream Event Downstream Event Creation Date Last Updated AOPs
2708 1527: Increase, Cell membrane depolarization 389: Increased, Intracellular Calcium overload Jul 25, 2022 Jul 25, 2022 None
2788 1527: Increase, Cell membrane depolarization 55: Cell injury/death Oct 19, 2022 Oct 19, 2022
3039 1527: Increase, Cell membrane depolarization 2187: Opening VGCCs Sep 14, 2023 Sep 14, 2023
890 870: Increase, Cell Proliferation 376: Increased, Induced Mutations in Critical Genes Nov 29, 2016 Dec 3, 2016 None
893 870: Increase, Cell Proliferation 876: Increase, Mutations in Critical Genes Nov 29, 2016 Dec 3, 2016
895 870: Increase, Cell Proliferation 872: Increase, Site of Contact Nasal Tumors Nov 29, 2016 Dec 1, 2016
1967 870: Increase, Cell Proliferation 1670: Lung cancer Jul 3, 2019 Jul 3, 2019
1980 870: Increase, Cell Proliferation 1556: Increase, lung cancer Aug 29, 2019 Jan 10, 2023
2419 870: Increase, Cell Proliferation 1090: Increased, mesotheliomas Jul 6, 2021 Jul 6, 2021
2819 870: Increase, Cell Proliferation 2083: Cataracts Dec 18, 2022 Mar 8, 2024
1247 1182: Increase, Cell Proliferation (Epithelial Cells) 1192: Increased, Ductal Hyperplasia Nov 29, 2016 Dec 3, 2016
1907 1182: Increase, Cell Proliferation (Epithelial Cells) 185: Increase, Mutations May 8, 2019 May 8, 2019
773 716: Increase, cell proliferation (hepatocytes) 774: Increase, Preneoplastic foci (hepatocytes) Nov 29, 2016 Feb 14, 2017
1239 716: Increase, cell proliferation (hepatocytes) 1171: Increase, Clonal Expansion of Altered Hepatic Foci Nov 29, 2016 Dec 3, 2016
2254 716: Increase, cell proliferation (hepatocytes) 719: Increase, hepatocellular adenomas and carcinomas Dec 31, 2020 Dec 31, 2020
1979 1636: Increase, Chromosomal aberrations 870: Increase, Cell Proliferation Aug 29, 2019 Mar 8, 2024
1985 1636: Increase, Chromosomal aberrations 1556: Increase, lung cancer Aug 29, 2019 Jan 10, 2023
637 621: Increase, cilia movement 622: Increased, locomotion Nov 29, 2016 Dec 3, 2016 None
639 621: Increase, cilia movement 624: Increased, foot detachment Nov 29, 2016 Dec 3, 2016 None
1178 621: Increase, cilia movement 1144: premature, spawning 1 Nov 29, 2016 Dec 3, 2016 None
1187 621: Increase, cilia movement 1146: premature, Spawning Nov 29, 2016 Dec 3, 2016 None
1217 621: Increase, cilia movement 1166: Increased, water pumping Nov 29, 2016 Dec 3, 2016 None
1218 621: Increase, cilia movement 1143: Depletion, energy reserves Nov 29, 2016 Dec 3, 2016 None
1321 621: Increase, cilia movement 1255: induced spawning Jan 13, 2017 Jan 13, 2017
1335 621: Increase, cilia movement 1257: Induced parturition Jan 30, 2017 Jan 30, 2017