| 2656 |
618: Decreased, Neuronal network function in adult brain |
1583: Sensory axonal peripheral neuropathy |
May 16, 2022 |
May 16, 2022 |
1 AOP
|
| 3072 |
618: Decreased, Neuronal network function in adult brain |
2150: Neurological disorder |
Oct 17, 2023 |
Oct 17, 2023 |
1 AOP
|
| 3073 |
618: Decreased, Neuronal network function in adult brain |
188: Neuroinflammation |
Oct 17, 2023 |
Oct 17, 2023 |
1 AOP
|
| 3074 |
618: Decreased, Neuronal network function in adult brain |
890: Degeneration of dopaminergic neurons of the nigrostriatal pathway |
Oct 17, 2023 |
Oct 17, 2023 |
None
|
| 3076 |
618: Decreased, Neuronal network function in adult brain |
637: impaired, Learning and memory |
Oct 17, 2023 |
Oct 17, 2023 |
1 AOP
|
| 1448 |
1330: Decreased, neuroplasticity |
1345: Increased, agitation |
Apr 14, 2017 |
Apr 14, 2017 |
3 AOPs
|
| 1449 |
1330: Decreased, neuroplasticity |
1346: Increased, depression |
Apr 14, 2017 |
Apr 14, 2017 |
3 AOPs
|
| 212 |
193: Decreased, Nitric Oxide |
166: Decreased, Long-term potentiation (LTP) |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 1084 |
1045: Decreased, Ovarian E2 |
1047: Increased, secretion of GnRH from hypothalamus |
Nov 29, 2016 |
Dec 3, 2016 |
None
|
| 1085 |
1045: Decreased, Ovarian E2 |
1056: Decrease, E2 blood concentrations at hypothalamus |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 2803 |
2074: Decrease overall oxygen binding capacity (methemocyanin formation) |
2076: Increase, hemocyanin mRNA |
Nov 16, 2022 |
Nov 16, 2022 |
1 AOP
|
| 1433 |
1324: Decreased, packaged serotonin |
1325: Decreased, synaptic release |
Apr 14, 2017 |
Apr 14, 2017 |
4 AOPs
|
| 503 |
216: Decreased, PCK1 expression (control point for glycolysis/gluconeogenesis pathway) |
327: Accumulation, Fatty acid |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 881 |
859: Decreased, Peroxisomal Fatty Acid Beta Oxidation of Fatty Acids |
860: Decreased, Mitochondrial Fatty Acid Beta Oxidation |
Nov 29, 2016 |
Nov 29, 2016 |
None
|
| 3289 |
2237: Decreased, Plasma sodium concentrations |
1768: Increase, Abnormal osmoregulation |
Jul 8, 2024 |
Dec 3, 2024 |
None
|
| 3346 |
2237: Decreased, Plasma sodium concentrations |
2261: Decreased, blood plasma volume |
Sep 20, 2024 |
Dec 3, 2024 |
1 AOP
|
| 1491 |
442: Decreased, Population trajectory |
351: Increased Mortality |
Apr 18, 2017 |
Apr 18, 2017 |
None
|
| 257 |
231: Decreased, PPAR-alpha activation |
140: Decreased, HSD17B10 expression |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 2042 |
231: Decreased, PPAR-alpha activation |
459: Increase, Liver steatosis |
Feb 22, 2020 |
Feb 22, 2020 |
None
|
| 259 |
232: Decreased, PPAR-beta activation |
140: Decreased, HSD17B10 expression |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 260 |
233: Decreased, PPAR-gamma activation |
140: Decreased, HSD17B10 expression |
Nov 29, 2016 |
Dec 3, 2016 |
1 AOP
|
| 3093 |
233: Decreased, PPAR-gamma activation |
1060: Alteration, lipid metabolism |
Oct 18, 2023 |
Oct 19, 2023 |
1 AOP
|
| 878 |
858: Decreased, PPARalpha transactivation of gene expression |
859: Decreased, Peroxisomal Fatty Acid Beta Oxidation of Fatty Acids |
Nov 29, 2016 |
Jun 2, 2017 |
None
|
| 879 |
858: Decreased, PPARalpha transactivation of gene expression |
860: Decreased, Mitochondrial Fatty Acid Beta Oxidation |
Nov 29, 2016 |
Jun 2, 2017 |
None
|
| 880 |
858: Decreased, PPARalpha transactivation of gene expression |
861: Decreased, Ketogenesis (production of ketone bodies) |
Nov 29, 2016 |
Jun 11, 2018 |
1 AOP
|