AOPs

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Showing 276 to 300 of 574 AOPs

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ID Title Point of Contact License MIE AO OECD Status OECD Project
325 Excessive reactive oxygen species leading to growth inhibition via uncoupling of oxidative phosphorylation and reduced cell growth You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
326 Excessive reactive oxygen species leading to growth inhibition via uncoupling of oxidative phosphorylation and reduced cell proliferation You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
327 Excessive reactive oxygen species production leading to mortality (1) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
328 Excessive reactive oxygen species production leading to mortality (2) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
329 Excessive reactive oxygen species production leading to mortality (3) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
330 Excessive reactive oxygen species production leading to mortality (4) You Song BY-SA 1115: Increase, Reactive oxygen species 350: Increase, Mortality
331 Excessive reactive oxygen species leading to growth inhibition via lipid peroxidation and cell death You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
332 Excessive reactive oxygen species leading to growth inhibition via lipid peroxidation and reduced cell growth You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
333 Excessive reactive oxygen species leading to growth inhibition via lipid peroxidation and reduced cell proliferation You Song BY-SA 1115: Increase, Reactive oxygen species 1521: Decrease, Growth
334 Glucocorticoid Receptor Agonism Leading to Impaired Fin Regeneration Alexander Cole BY-SA 122: Increase, Glucocorticoid receptor activation 360: Decrease, Population growth rate
335 AOP for urothelial carcinogenesis due to chemical cytotoxicity by mitochondrial impairment Nathalia Pereira Souza BY-SA 177: Increase, Mitochondrial dysfunction 1763: Urothelial Tumor
336 DNA methyltransferase inhibition leading to population decline (1) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
337 DNA methyltransferase inhibition leading to population decline (2) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
338 DNA methyltransferase inhibition leading to population decline (3) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
339 DNA methyltransferase inhibition leading to population decline (4) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
340 DNA methyltransferase inhibition leading to transgenerational effects (1) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
341 DNA methyltransferase inhibition leading to transgenerational effects (2) You Song BY-SA 1619: Increase, DNA methyltransferase inhibition
342 Ecdysone receptor hyperactivation leading to mortality via mis-timed activation of nuclear receptor cascade You Song BY-SA 103: Increase, Ecdysone receptor hyperactivation
343 Ecdysone receptor antagonism leading to mortality via mis-timed ecdysone receptor-responsive nuclear receptor cascade You Song BY-SA 2374: Increase, Ecdysone receptor antagonism
344 Androgen receptor (AR) antagonism leading to nipple retention (NR) in male (mammalian) offspring Terje Svingen BY-SA 26: Antagonism, Androgen receptor 1786: Nipple retention (NR), increased Under Development 1.108
345 Androgen receptor (AR) antagonism leading to decreased fertility in females Terje Svingen BY-SA 26: Antagonism, Androgen receptor Under Development 1.109
346 Aromatase inhibition leads to male-biased sex ratio via impacts on gonad differentiation Kelvin Santana Rodriguez BY-SA 36: Inhibition, Aromatase 360: Decrease, Population growth rate WPHA/WNT Endorsed 1.12
347 Toll-like receptor 4 activation and peroxisome proliferator-activated receptor gamma inactivation leading to pulmonary fibrosis Seokjoo Yoon BY-SA 1458: Pulmonary fibrosis
348 Inhibition of 11β-Hydroxysteroid Dehydrogenase leading to decreased population trajectory Young Jun Kim BY-SA 1799: Inhibition of 11β-HSD 360: Decrease, Population growth rate Under Development 1.93
349 Inhibition of 11β-hydroxylase leading to decresed population trajectory Young Jun Kim BY-SA 1796: 11β-hydroxylase inhibition 360: Decrease, Population growth rate Under Development 1.93