API

Relationship: 1030

Title

?

Reduced, Young of year survival leads to Decrease, Population trajectory

Upstream event

?

Reduced, Young of year survival

Downstream event

?


Decrease, Population trajectory

Key Event Relationship Overview

?

AOPs Referencing Relationship

?

AOP Name Adjacency Weight of Evidence Quantitative Understanding
Deiodinase 2 inhibition leading to reduced young of year survival via posterior swim bladder inflation adjacent
Deiodinase 2 inhibition leading to reduced young of year survival via anterior swim bladder inflation adjacent
Deiodinase 1 inhibition leading to reduced young of year survival via posterior swim bladder inflation adjacent
Deiodinase 1 inhibition leading to reduced young of year survival via anterior swim bladder inflation adjacent
Thyroperoxidase inhibition leading to reduced young of year survival via anterior swim bladder inflation adjacent

Taxonomic Applicability

?

Term Scientific Term Evidence Link
all species all species NCBI

Sex Applicability

?

Life Stage Applicability

?

Key Event Relationship Description

?

If young of year survival is reduced, ultimately the population trajectory will decrease.

Evidence Supporting this KER

?

Survival rate is an obvious determinant of population size and is therefore included in population modeling (e.g., Miller et al., 2020).

Biological Plausibility

?

It is widely accepted that if young of year survival is reduced, the population trajectory will eventually decrease.

Empirical Evidence

?

Uncertainties and Inconsistencies

?

Quantitative Understanding of the Linkage

?

Response-response Relationship

?

Time-scale

?

Known modulating factors

?

Known Feedforward/Feedback loops influencing this KER

?

Domain of Applicability

?

References

?

Miller, D.H., Clark, B.W., Nacci, D.E. 2020. A multidimensional density dependent matrix population model for assessing risk of stressors to fish populations. Ecotoxicology and environmental safety 201, 110786