API

Relationship: 2128

Title

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Decrease, AR activation leads to decrease, transcription of genes by AR

Upstream event

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Decrease, AR activation

Downstream event

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decrease, transcription of genes by AR

Key Event Relationship Overview

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AOPs Referencing Relationship

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Taxonomic Applicability

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Term Scientific Term Evidence Link
human Homo sapiens High NCBI
mouse Mus musculus High NCBI
human and other cells in culture human and other cells in culture High NCBI
rat Rattus norvegicus High NCBI

Sex Applicability

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Sex Evidence
Male High
Female High

Life Stage Applicability

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Term Evidence
During development and at adulthood High

Key Event Relationship Description

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Evidence Supporting this KER

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Biological Plausibility

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Empirical Evidence

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Uncertainties and Inconsistencies

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Quantitative Understanding of the Linkage

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Response-response Relationship

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Time-scale

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Known modulating factors

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Known Feedforward/Feedback loops influencing this KER

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Domain of Applicability

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References

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