API

Relationship: 930

Title

?

Bile accumulation, Pathological condition leads to Production, Reactive oxygen species

Upstream event

?

Bile accumulation, Pathological condition

Downstream event

?


Production, Reactive oxygen species

Key Event Relationship Overview

?


AOPs Referencing Relationship

?

AOP Name Directness Weight of Evidence Quantitative Understanding
Cholestatic Liver Injury induced by Inhibition of the Bile Salt Export Pump (ABCB11) directly leads to Strong

Taxonomic Applicability

?


Sex Applicability

?


Life Stage Applicability

?


How Does This Key Event Relationship Work

?


Weight of Evidence

?


Biological Plausibility

?

Empirical Support for Linkage

?

Uncertainties or Inconsistencies

?

Quantitative Understanding of the Linkage

?


Evidence Supporting Taxonomic Applicability

?


References

?