AOPs

OECD View API
Searches both title and fulltext content
Takes you to the requested AOP
Clear Search Terms Clears search terms and filters

Showing 176 to 200 of 574 AOPs

Clear Table Filters
ID Title Point of Contact License MIE AO OECD Status OECD Project
211 Handbook development AOP Dan Villeneuve BY-SA None None
212 Histone deacetylase inhibition leading to testicular atrophy Shihori Tanabe BY-SA 1502: Histone deacetylase inhibition 1506: Testicular atrophy WPHA/WNT Endorsed 1.52
213 Inhibition of fatty acid beta oxidation leading to nonalcoholic steatohepatitis (NASH) Lyle Burgoon Open for adoption 1490: Inhibition, Fatty Acid Beta Oxidation 1489: Increase, Steatohepatitis
214 Network of SSRIs (selective serotonin reuptake inhibitors) Lyle Burgoon Open for adoption None
215 Molecular events lead to epilepsy Lyle Burgoon Open for adoption None
216 Deposition of energy leading to population decline via DNA strand breaks and follicular atresia Knut Erik Tollefsen BY-SA 1686: Deposition of Energy
217 Gastric ulcer formation Lyle Burgoon Open for adoption None
218 Inhibition of CYP7B activity leads to decreased reproductive success via decreased locomotor activity Florence Pagé-Larivière BY-SA 1386: CYP7B activity, inhibition 360: Decrease, Population growth rate
219 Inhibition of CYP7B activity leads to decreased reproductive success via decreased sexual behavior Florence Pagé-Larivière BY-SA 1386: CYP7B activity, inhibition 360: Decrease, Population growth rate
220 Cyp2E1 Activation Leading to Liver Cancer Francina Webster BY-SA 1391: Activation of Cyp2E1 1395: Liver Cancer WPHA/WNT Endorsed 1.24
221 Mental stress to depression Lyle Burgoon Open for adoption 1396: Increased, glucocorticoid receptor activity 1346: Increased, depression
222 Mental stress to agitation Lyle Burgoon Open for adoption 1396: Increased, glucocorticoid receptor activity 1345: Increased, agitation
223 Serotonin transporter activation to seizure Lyle Burgoon Open for adoption 1397: Increased, serotonin transporter activity 1344: Increased, seizure
224 Serotonin transporter activation to depression Lyle Burgoon Open for adoption 1397: Increased, serotonin transporter activity 1346: Increased, depression
225 Serotonin transporter activation to agitation Lyle Burgoon Open for adoption None 1345: Increased, agitation
226 SSRI (Selective serotonin reuptake inhibitor) to hypertension Lyle Burgoon Open for adoption 1317: Decreased, serotonin transporter activity 1343: Increase, hypertension
227 NSAID induced PTGS1 inactivation to gastric ulcer Lyle Burgoon Open for adoption 1402: Reduced, PTGS1 function 1385: Activated, gastric ulcer formation
228 NSAID induced PTGS2 inactivation to gastric ulcer Lyle Burgoon Open for adoption 1408: Reduced, PTGS2 function 1385: Activated, gastric ulcer formation
229 Helicobacter pylori to gastric ulcer Lyle Burgoon Open for adoption 1412: Helicobacter pylori infection 1385: Activated, gastric ulcer formation
230 presynaptic neuron 1 activation to epilepsy Lyle Burgoon Open for adoption 1349: Activated, presynaptic neuron 1 1363: Increased, epilepsy
231 presynaptic neuron 2 repression to epilepsy Lyle Burgoon Open for adoption 1413: Reduced, presynaptic neuron 2 activity 1363: Increased, epilepsy
232 NFE2/Nrf2 repression to steatosis Lyle Burgoon Open for adoption 1417: NFE2/Nrf2 repression 459: Increase, Liver steatosis
233 Mu Opioid Receptor Agonism leading to Analgesia via K Channel Opening Timothy Allen BY-SA 1425: Mu Opioid Receptor Agonism 1428: Analgesia
234 Mu Opioid Receptor Agonism leading to Analgesia via Ca Channel Inhibition Timothy Allen BY-SA 1425: Mu Opioid Receptor Agonism 1428: Analgesia
235 Serotonin 1A Receptor Agonism leading to Anti-depressant Activity via K Channel Opening Timothy Allen BY-SA 1431: Serotonin 1A Receptor Agonism 1432: Anti-depressant Activity