API

Aop: 243

AOP Title

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Alkylation of DNA in male prebiotic germ cells leading to heritable mutations

Short name:

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DNA Alkylation

Authors

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Point of Contact

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Kristie Sullivan

Contributors

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  • Kristie Sullivan

Status

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Author status OECD status OECD project SAAOP status
Under development: Not open for comment. Do not cite


This AOP was last modified on August 20, 2017 13:22

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Abstract

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Background (optional)

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Summary of the AOP

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Stressors

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Molecular Initiating Event

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Key Events

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Adverse Outcome

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Relationships Between Two Key Events (Including MIEs and AOs)

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Network View

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Life Stage Applicability

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Taxonomic Applicability

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Sex Applicability

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Graphical Representation

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Overall Assessment of the AOP

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Domain of Applicability

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Essentiality of the Key Events

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Weight of Evidence Summary

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Quantitative Considerations

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Considerations for Potential Applications of the AOP (optional)

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References

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