AOP-Wiki

API

All Key Events

Showing 1001 to 1025 of 1939 Key Events

ID	Title	Event Component Count	Biological Organization	Created At	Last Updated	AOPs

1390	Sexual behavior, decreased Short Name Sexual behavior, decreased	0	Individual	May 3, 2017	May 17, 2017	219: Inhibition of CYP7B activity leads to decreased reproductive success via decreased sexual behavior
1389	Locomotor activity, decreased Short Name Locomotor activity, decreased	0	Individual	May 2, 2017	May 18, 2017	218: Inhibition of CYP7B activity leads to decreased reproductive success via decreased locomotor activity
1388	Dopamine release in the brain, decreased Short Name	0	Tissue	May 2, 2017	May 17, 2017	2 AOPs 218: Inhibition of CYP7B activity leads to decreased reproductive success via decreased locomotor activity 219: Inhibition of CYP7B activity leads to decreased reproductive success via decreased sexual behavior
1387	7α-hydroxypregnenolone synthesis in the brain, decreased Short Name	0	Cellular	May 2, 2017	May 17, 2017	2 AOPs 218: Inhibition of CYP7B activity leads to decreased reproductive success via decreased locomotor activity 219: Inhibition of CYP7B activity leads to decreased reproductive success via decreased sexual behavior
1386	CYP7B activity, inhibition Short Name CYP7B activity, inhibition	0	Molecular	May 2, 2017	May 17, 2017	2 AOPs 218: Inhibition of CYP7B activity leads to decreased reproductive success via decreased locomotor activity 219: Inhibition of CYP7B activity leads to decreased reproductive success via decreased sexual behavior
1385	Activated, gastric ulcer formation Short Name Activated, gastric ulcer formation	0	Organ	Apr 17, 2017	Jun 2, 2017	4 AOPs 217: Gastric ulcer formation 227: NSAID induced PTGS1 inactivation to gastric ulcer 228: NSAID induced PTGS2 inactivation to gastric ulcer 229: Helicobacter pylori to gastric ulcer
1384	Increase, ammonium (NH4+) Short Name Increase, ammonium (NH4+)	0	Molecular	Apr 17, 2017	Apr 17, 2017	2 AOPs 217: Gastric ulcer formation 229: Helicobacter pylori to gastric ulcer
1383	Activate, phospholipase Short Name Activate, phospholipase	0	Molecular	Apr 17, 2017	Apr 17, 2017	2 AOPs 217: Gastric ulcer formation 229: Helicobacter pylori to gastric ulcer
1382	Decrease, surfactant Short Name Decrease, surfactant	0	Molecular	Apr 17, 2017	Apr 17, 2017	2 AOPs 217: Gastric ulcer formation 229: Helicobacter pylori to gastric ulcer
1381	Increase, surfactant Short Name Increase, surfactant	0	Molecular	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1380	Activate, mucosal defense Short Name Activate, mucosal defense	0	Tissue	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1379	Activate, leukocyte Short Name Activate, leukocyte	0	Cellular	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1378	Increase, leukocyte adherence Short Name Increase, leukocyte adherence	0	Tissue	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1377	Decrease, leukocyte adherence Short Name Decrease, leukocyte adherence	0	Tissue	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1376	Increase, angiogenesis Short Name Increase, angiogenesis	1	Tissue	Apr 17, 2017	Feb 29, 2024	2 AOPs 217: Gastric ulcer formation 439: Activation of the AhR leading to metastatic breast cancer
1375	Increase, platelet aggregation Short Name Increase, platelet aggregation	0	Tissue	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1374	Increase, mucosal blood flow Short Name Increase, mucosal blood flow	0	Tissue	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1373	Increase, mucous Short Name Increase, mucous	0	Molecular	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1372	Increase, bicarbonate Short Name Increase, bicarbonate	0	Molecular	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1371	Inhibition, PTGS-2 (Prostaglandin-endoperoxide synthase 2) Short Name	0	Molecular	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1370	Activation, PTGS-2 (Prostaglandin-endoperoxide synthase 2) Short Name Activation, PTGS-2	0	Molecular	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1369	Activation, PTGS-1 (Prostaglandin-endoperoxide synthase 1) Short Name Activation, PTGS-1	0	Molecular	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1368	Inhibition, PTGS-1 (Prostaglandin-endoperoxide synthase 1) Short Name Inhibition, PTGS-1	0	Molecular	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1367	Inhibit, gastric ulcer formation Short Name Inhibit, gastric ulcer formation	0	Organ	Apr 17, 2017	Apr 17, 2017	217: Gastric ulcer formation
1366	Decrease, Oogenesis Short Name Decrease, Oogenesis	0	Organ	Apr 15, 2017	Apr 30, 2020	9 AOPs 336: DNA methyltransferase inhibition leading to population decline (1) 337: DNA methyltransferase inhibition leading to population decline (2) 338: DNA methyltransferase inhibition leading to population decline (3) 339: DNA methyltransferase inhibition leading to population decline (4) 216: Deposition of energy leading to population decline via DNA strand breaks and follicular atresia 238: Deposition of energy leading to population decline via DNA strand breaks and oocyte apoptosis 299: Deposition of energy leading to population decline via DNA oxidation and follicular atresia 311: Deposition of energy leading to population decline via DNA oxidation and oocyte apoptosis 396: Deposition of ionizing energy leads to population decline via impaired meiosis